cortexmap

CLI for lesion unfolding on mouse cerebral cortex.

Usage no npm install needed!

<script type="module">
  import cortexmap from 'https://cdn.skypack.dev/cortexmap';
</script>

README

CortexMap

The localization of traumatic brain injury (TBI) lesions directly correlates with motor disabilities and cognitive impairment. By unfolding magnetic resonance (MR) images of a lesioned rat cortex on a two-dimensional (2D) cytoarchitecture map of the cortex, it is possible to predict the severity of the resulting cognitive and behavioral impairment.

CortexMap is a web application to estimate the location of the lesion on mouse cerebral cortex caused by TBI induced by lateral fluid-percussion injury. The application unfolds user-determined TBI lesion measurements, e.g., from histologic sections to a reference template, and estimates the total lesion area, including the percentage of cortex damaged in different cytoarchitectural cortical regions.